Tangential Flow Ultrafiltration yog dab tsi? Cov ntawv thov yog dab tsi?
Tangential flow yog hais txog daim ntawv pom nyob rau hauv uas cov kev taw qhia ntawm cov kua ntws yog perpendicular mus rau cov kev taw qhia ntawm filtration.
Ib txwm ua kua dej tuag-kawg pom, tseem hu ua ntsug filtration, yog daim ntawv pom pom los ntawm feem ntau cov microporous pom, nrog rau kev ua kom tsis muaj menyuam. Cov kev taw qhia ntws ntawm cov kua yog ua raws li kev pom kev pom. Lub thickness ntawm lub ncuav mog qab zib lim los yog gel txheej tsub kom maj mam, thiab tus nqi ntws maj mam txo. Thaum lub lim nruab nrab yog ib qho ultrafiltration membrane los yog microfiltration membrane nrog me me pore loj, thaum cov ntsiab lus ntawm cov khoom noj nyob rau hauv cov kua zaub yog siab, txoj kev tuag-kawg pom yuav txo tus nqi ntws sai, yog li qhov tuag-kawg pom tsuas yog cov txheej txheem. me me ntawm cov kua pub.
Tangential flow ultrafiltration yog hais txog daim ntawv pom nyob rau hauv uas cov kua ntws cov kev taw qhia yog perpendicular mus rau lub pom kev taw qhia, uas yog, cov kua ntws nyob rau hauv ib tug kev taw qhia parallel mus rau daim nyias nyias, thiab lub nto ntawm daim nyias nyias yog ntxuav thaum lim, thiaj li tsis muaj condensation. yuav tsim nyob rau saum npoo ntawm daim nyias nyias. Cov kua nplaum txheej tuav ruaj khov ultrafiltration tus nqi. Nws yog dav siv nyob rau hauv kev tshawb fawb thiab kev loj hlob, pilot test thiab industrial ntau lawm. Rau cov khoom siv loj-loj ua kua pom, txoj kev tangential flow ultrafiltration yog saws. Cov kua dej ua kom muaj zog shear rau saum npoo ntawm lub lim nruab nrab, uas txo cov ncuav qab zib lim los yog gel. Lub tsub zuj zuj ntawm cov khaubncaws sab nraud povtseg kom ruaj khov ceev ceev.
Hauv kev lag luam biopharmaceutical, raws li qhov sib txawv ntawm cov membrane modules, ob hom ultrafiltration tshuab feem ntau yog siv: membrane pob hom thiab hollow fiber hom. Feem ntau hais lus: hollow fibers yog tsim nyog rau cov qauv loj/dirtier (xws li cov khoom-kua sib cais, cell lysate, thiab lwm yam), hos membrane cassettes yog tsim nyog rau cov qauv huv si (xws li protein concentration, piv txwv tsis pub pauv los yog protein renaturation) Tos).
