Lub hauv paus ntsiab lus ntawm tangential flow ultrafiltration? Yuav ua li cas cais biomolecules
Nyob rau hauv tangential flow (tseem hu ua cross flow) ultrafiltration, lub twj tso kua mis thawb cov kua los ntawm qhov chaw ntawm lub lim membrane kom ntxuav tawm cov ntxiab molecules, thiaj li txo qis qhov ntsuas ntawm lub lim membrane. Lub siab ze ntawm lub lim membrane yog generated nyob rau hauv residual logistics kom solutes thiab me me molecules dhau los ntawm lub lim membrane. Ua li no, kev lim dej tuaj yeem ua tiav. Kev simulation kev sib cais ntawm cov xuab zeb thiab pebbles los ntawm subdivision screen yog pab kom nkag siab txog cov txheej txheem ntawm tangential flow ultrafiltration: lub qhov screen cim lub qhov hws ntawm lub lim membrane, thaum xuab zeb thiab pebbles cim lub molecules yuav tsum tau sib cais. Hauv DC pom, cov xuab zeb pebble sib tov yog yuam kom txav mus rau qhov screen qhov. Raws li qee cov xuab zeb me me poob los ntawm qhov screen, ib txheej pebble yog tsim rau ntawm qhov screen, tiv thaiv cov xuab zeb saum toj kawg nkaus ntawm kev txav mus rau qhov screen thiab dhau ntawm qhov screen mesh. Nyob rau hauv DC filtration, nce lub siab tuaj yeem tsuas yog siv lub zog ntawm qhov sib tov, uas tsis tsim nyog rau kev txhawb nqa kev sib cais; Nyob rau hauv sib piv, nyob rau hauv lub tangential flow ultrafiltration hom, lub tsim ntawm limiting txheej yog tiv thaiv los ntawm recirculation ntawm cov sib tov, uas yog zoo li kev co kom tshem tawm cov pebbles thaiv lub screen mesh, thiaj li hais tias cov xuab zeb hais nyob rau sab saum toj ntawm cov sib tov. poob thiab dhau ntawm qhov screen mesh. Yog li ntawd, kev siv tangential flow ultrafiltration rau biomolecular sib cais muaj ntau dua efficiency thiab ceev concentration los yog ntxuav filtration ceev.
