Cov Txheej Txheem Rau Ntxuav Tangential Flow Filter Membrane
Covtxoj kev los ntxuav tangential flow filter membrane
Hauv kev lag luam biopharmaceutical, tangential flow lim membrane cassettes lossis hollow fibers tau siv dav hauv kev nthuav dav, tsom, desalting, thiab tshem tawm endotoxins. Raws li ib yam ntawm precision filtration membrane, lawv muaj peev xwm ua tau zoo thiab ceev ceev cais cov hom phiaj thiab impurities, tab sis tom qab siv, ntau yam kuab paug yuav tsub kom nyob rau hauv daim nyias nyias, uas ua rau txo membrane kev ua tau zoo thiab shortened membrane lub neej. Txhawm rau kom rov ua haujlwm ntawm lub lim membrane, tiv thaiv lub lim membrane los ntawm kev sib kis thiab thaiv, thiab tsis txhob hla kev sib kis ntawm cov khoom siv, ntxuav cov lim membrane tom qab siv yog ib qho tseem ceeb heev ntawm kev saib xyuas txhua hnub.
Yog li ntawd, nws yog qhov tseem ceeb tshaj plaws los tham txog cov txheej txheem thev naus laus zis los kho cov pa phem ntawm lim membrane. Kab lus no yuav ua kom paub ntau yam kev tu vaj tse ntawm lim membrane.
Lub hom phiaj ntawm kev tu daim nyias nyias yog siv txoj kev tu kom tsim nyog los ntxuav thiab rov tsim cov kuab paug, rhuav tshem cov kua nplaum adsorption txheej ntawm daim nyias nyias, tshem tawm cov impurities hauv daim nyias nyias, thiab rov ua dua daim nyias nyias mus rau qhov qub flux ntau npaum li cas. ua tau. Filter membrane tu tshuab feem ntau suav nrog kev tu lub cev, tshuaj ntxuav thiab tshuaj lom neeg.
Kev ntxuav lub cev
Kev siv thev naus laus zis ntawm kev tu lub cev yog hydraulic tu tshuab thiab roj-kua mem tes tshuab, uas yog cov txheej txheem tu yooj yim rau thawj theem ntawm lim membrane cov pa phem, feem ntau yog siv los tshem tawm cov pa phem ntawm lim membrane. Hydraulic tu tshuab feem ntau suav nrog cov txheej txheem qis-siab ceev ceev, rov qab siab tu txoj kev, isobaric tu txoj kev thiab tsis zoo siab tu txoj kev, thiab lwm yam, feem ntau yog hais txog cov txheej txheem ntawm kev tshem tawm cov pa phem los ntawm kev siv roj, dej lossis cov kua dej sib xyaw. dej thiab cua nyob rau hauv rov qab los yog tangent kev taw qhia. Gas-kua pulse tu tshuab yog coj cov roj kub siab mus rau hauv qhov sib txawv ntawm cov khoom siv lim membrane kom nthuav dav lub qhov membrane, thiab tom qab ntawd cov pa phem raug ntxuav tawm los ntawm cov kua. Tsis tas li ntawd, cov cuab yeej tu lub cev xws li kev tu ultrasonic, kev co txhua yam, kev tu lub pob sponge thiab pulsed electric teb tu kuj tau siv.
Tshuaj ntxuav
Thaum cov nyhuv ntawm kev tu lub cev tsis zoo, kev siv tshuaj lom neeg tuaj yeem siv tau, thiab txoj kev no yog txoj kev siv ntau tshaj plaws los ntxuav cov kab mob lom. Kev siv tshuaj ntxuav yog siv cov tshuaj tiv thaiv ntawm cov tshuaj ntxuav thiab daim nyias nyias pores thiab deg pollutants kom tshem tawm lub cev tu nyuaj kom tshem tawm cov pa phem. Kev tu tshuaj yuav tsum xav txog yam xws li lub sijhawm tu, qhov kub thiab txias thiab hom tshuaj. Hauv kev ua haujlwm tiag tiag ntawm lub lim membrane system, cov tshuaj tsis muaj tshuaj lom thiab tsis muaj kev puas tsuaj nrog kev tu zoo yuav tsum raug xaiv raws li cov khoom siv thiab cov khoom siv membrane kho.
Lub hauv paus ntsiab lus rau xaiv cov tshuaj ntxuav cov neeg ua haujlwm:
Tsis muaj tshuaj lom neeg muaj peev xwm tshwm sim nrog ultrafiltration membrane thiab lwm yam ntaub ntawv ntawm cov khoom.
Kev xaiv cov tshuaj kom tsis txhob muaj cov pa phem thib ob ultrafiltration membrane tu.
Acid tshuaj ntxuav: feem ntau siv cov kua qaub yog hydrochloric acid, citric acid, oxalic acid, thiab lwm yam., PH ntawm cov tshuaj npaj yog {{0}}} (qhov tshwj xeeb PH nqi nyob ntawm cov khoom siv), lub voj voog tu {{ 3}}.5-1h los yog tsau 0.5-1h ua ntej lub voj voog tu, uas tuaj yeem tshem tawm cov pa phem (DNA, polysaccharide, kab mob hlwb thiab cov av tsis muaj zog).
Alkali tshuaj ntxuav: Lub ntsiab siv alkali yog NaOH, qhov concentration ntawm cov tshuaj npaj yog {{0}}.5M, PH=10-12 (qhov tshwj xeeb concentration thiab PH tus nqi nyob ntawm seb hom khoom), lub voj voog ntxuav 0.5-1h los yog tsau 0.5-1h ua ntej lub voj voog tu, uas tuaj yeem tshem tawm cov pa phem (protein, lipid thiab polysaccharide compounds).
Surfactant: Feem ntau siv surfactants yog SDS (sodium dodecyl sulfonate), Tween 80, Triton X-100 (non-ionic surfactant), voj voog tu 0.5-1h los yog tsau 0. Yuav tsum tau ua ke nrog lwm cov tshuaj ntxuav.
Oxidant ntxuav: Thaum cov kua qaub-puag thiab surfactant tsis ua haujlwm, 200-400mg/L active tshuaj chlorine (500-1000mg/L NaClO aqueous tov) yuav siv tau, PH=10-11, cyclic tu {{ 4}}. Tsis tas li ntawd, 1-3% H2O2 thiab poov tshuaj permanganate kuj qhia tau tias muaj kev tu kom zoo hauv qee lub sijhawm. H2O2 thiab NaClO feem ntau yog siv cov fungicides.
0.5M NaOH+200-400 PPM NaClO (25-45degree), uas yog tus neeg saib xyuas zoo tshaj plaws rau cov kab mob lom.NaOH tuaj yeem ua tau zoo hydrolyze feem ntau cov proteins, lipids thiab polysaccharide compounds. Ntxiv NaClO rau NaOH tshuaj tuaj yeem txhim kho kev tu lub peev xwm. NaClO reagent tuaj yeem oxidize thiab degrade protein av thiab lwm yam organic av tsis cuam tshuam rau saum npoo ntawm stainless hlau. Cov txheej txheem tu ib txwm yog kev tu lub voj voog {{0}}.5-1h los yog ntub dej 0.5-1h thiab tom qab ntawd ntxuav lub voj voog.
Kev tu huv
Kev khiav hauj lwm xws li kev khiav hauj lwm siab sib txawv, lub sij hawm khiav hauj lwm, kev khiav hauj lwm kub thiab inlet flow rate yog ib qho tseem ceeb cuam tshuam cov nyhuv tu thaum lub sij hawm ntxuav.
Raws li qhov xwm txheej ib txwm muaj, tus nqi nkag nkag yog tswj ntawm {{0}}L / min / m², qhov ntsuas kub yog tswj ntawm 20-50 degree , thiab lub sijhawm ntxuav yog tswj ntawm {{4} } 5-1 0h. Rau kev tu lub siab sib txawv, nws feem ntau pom zoo kom ncav cuag 30-50% ntawm qhov nkag nkag los ntawm tus nqi ntws. Vim tias qhov pore loj ntawm lub lim membrane sib txawv, thiab nrog rau kev siv cov lim membrane, qhov kev tu siab sib txawv tsis meej, yog li tsis txhob ua piv txwv kom ntxaws. Lus Cim: Feem ntau, TMP yuav tsum tsis pub tshaj 1.5bar thiab inlet siab yuav tsum tsis txhob tshaj 2bar. Yog tias thaum lub sij hawm thawj zaug ntxuav, lub siab pub tuaj yeem tswj tau qis dua 1bar, thiab lub siab rov qab tuaj yeem tswj tau ntawm li 0.5bar.
Txoj kev pom zoo rau kev ntxuav cov kab mob lom lom
Raws li qhov xwm txheej ib txwm muaj, cov khoom siv roj ntsha feem ntau tuaj yeem ntxuav tau tag nrho ntawm chav tsev kub los ntawm kev siv {{0}}.5M NaOH tov rau 0.5-10h.
Nov yog qee txoj kev ntxuav tshwj xeeb.
Kev tu tsiaj txhu
Kev tu tsiaj yog hais txog kev tshem tawm lossis decomposition ntawm cov pa phem xws li polysaccharides thiab cov proteins hauv cov khoom qias neeg ntawm cov lim membrane los ntawm cov tshuaj lom neeg lossis cov enzymes uas muaj kev ua haujlwm lom lom.
Enzyme detergent: xws li 0. Vim tias cov tshuaj tiv thaiv enzyme yuav siv sij hawm qee lub sijhawm, thiab feem ntau cov tshuaj tiv thaiv tsis tiav, thiab nws kuj yog cov protein, nws yuav tsim cov pa phem tshiab, yog li nws yuav tsum tau ntxuav dua nrog lwm cov tshuaj ntxuav, thiab yog li ntawd, kev siv cov tshuaj ntxuav tes enzyme yog tsim nyog. qhov tsawg tshaj plaws pom zoo ntawm tag nrho cov tshuaj ntxuav.
Hais txog Guidling
Guidling Technology yog lub teb chaws high-tech enterprise tsom rau biopharmaceuticals, cell culture, purification thiab concentration ntawm biomedicine, kuaj mob thiab muaj kua. Peb tau ua tiav cov khoom siv lim dej centrifugal, ultrafiltration & microfiltration cassettes, cov kab mob lim, TFF system, qhov tob lim, hollow fiber, thiab lwm yam. Uas tau raws li daim ntawv thov scenarios ntawm biopharmaceuticals, kab lis kev cai ntawm tes, thiab lwm yam. Peb cov membranes thiab cov lim dej lim tau dav siv hauv kev sib xyaw, kev rho tawm thiab kev sib cais ntawm kev pom ua ntej, microfiltration, ultrafiltration thiab nanofiltration. Peb cov kab ntau cov khoom, los ntawm me me, ib leeg-siv kuaj pom mus rau ntau lawm filtration systems, sterility kuaj, fermentation, cell kab lis kev cai thiab lwm yam, ua tau raws li cov kev xav tau ntawm kev sim thiab ntau lawm. Guidling Technology tab tom tos ntsoov rau kev koom tes nrog koj!