Thaum twg TFF siv?

Tangential flow filtration yog siv nyob rau hauv concentration thiab diafiltration txheej txheem.

Concentration - Ua kom cov concentration ntawm cov tshuaj los ntawm kev tshem tawm cov kua dej thaum khaws cov kua molecules. Cov txheej txheem no yog ua los ntawm kev xaiv lub lim me me dua li cov kua dej molecules kom tso cai rau kev khaws cia siab dua ntawm cov kua dej molecules.

Diafiltration - Kev sib cais ntawm cov khoom me me thiab loj, tawm hauv cov khoom me me tom qab yam tsis hloov tag nrho cov concentration ntawm qhov kawg los ntawm kev ntxuav tawm cov ntsev ntxiv nrog lwm qhov tsis. Cov txheej txheem no tseem tuaj yeem txo qhov concentration ntawm cov tshuaj los ntawm kev ntxuav tawm cov ntsev ntxiv nrog dej.

Cov ntawv thov tshwj xeeb ntawm TFF suav nrog, tab sis tsis txwv rau:

Pre-filtration tivthaiv WFI systems kom tshem tawm endotoxins.

Rov kho cov kab mob kab mob thiab kab mob.

Tshem tawm PVA uas raug tshem tawm los ntawm excipient los ntawm nanoparticles thaum thauj tshuaj.