Dab tsi yog qhov tseem ceeb ntawm Tangential Flow Filtration Technology
Thaum ua haujlwm TFF, peb feem ntau ntsib qee qhov teeb meem: piv txwv li, tus nqi rov qab ntawm lub hom phiaj protein tsawg, thiab lub siab nkag siab yuav nce ntxiv tom qab pom lub sijhawm. Lub sijhawm no, ob peb qhov tseem ceeb ntawm tangential flow filtration thiab lawv cov kev sib raug zoo yuav tsum tau qhia meej kom paub meej tias cov kev sim uas haum rau cov qauv tuaj yeem txiav txim siab los ntawm kev tshawb nrhiav thiab ua kom zoo dua qhov kev sim. Cov kev ntsuas no tau sau tseg rau hauv 2 qhov ntsuas siab thiab 2 qhov ntsuas tus nqi ntws.
Qhov sib txawv ntawm qhov siab yog qhov sib txawv ntawm lub siab inlet thiab lub qhov hluav taws xob siab. Transmembrane siab (TMP) yog hais txog qhov nruab nrab siab qhov sib txawv nruab nrab ntawm cov dej ntws thiab qis ntawm cov lim membrane (TMP =} (PF plus PR) / 2-pp). Cov kev sim TFF peb tsom rau yog qhov sib txawv siab, transmembrane siab, tangential tshaj tawm thiab lwm yam. Cov kev ntsuas no zoo sib xws. Lub siab sib txawv txiav txim siab qhov tangential flow thiab tangential flow. Thaum lub siab sib txawv tas li, tangential flow thiab tangential flow yog tas li, thiab lub siab transmembrane tswj qhov ceev ntawm cov kua pom.
Yog li ntawd, lub inlet siab thiab rov qab siab yuav tsum tau tswj. Ob lub siab no txiav txim siab TMP thiab qhov sib txawv ntawm qhov siab. Thaum lub siab sib txawv / tangential ntws tas li, TMP dhau los ua qhov tseem ceeb hauv cov txheej txheem tangential ntws, uas yuav tsum tau ua kom zoo.
Tangential flow yog qhov tshaj tawm ntawm cov kua ntws ntawm daim nyias nyias. Nws yog siv los ntxuav cov khoom kom tsis txhob muaj cov khoom sib txuam ntawm qhov chaw ntawm zaj duab xis. Cov khoom raug tshem tawm los ntawm daim nyias nyias los ntawm kev ua haujlwm scouring los ntawm tangential ntws. Inlet siab thiab tangential flow (tangential dej ntws los yog rov ntws). Thaum qhov tangential ntws nce, qhov sib txawv ntawm qhov nkag thiab rov qab xaus Δ P kuj nce. Yog hais tias qhov tangential ntws yog ob npaug, qhov kawg Δ P kuj yog ob npaug. Ib feem kaw qhov rov qab valve yuav nce TMP thiab nws thiaj li thawb cov kua los ntawm daim nyias nyias. Lub sijhawm ntau lub tshev valve raug kaw, qhov ntau dua TMP, yog li lub sijhawm ntau cov kua hla dhau. Rau feem ntau cov ntawv thov ultrafiltration, osmotic valve qhib.